Professor James McCarthy is a clinician scientist with an outstanding record of achievement in translational research in parasitic diseases. Although his most notable recent achievements relate to the development of a unique malaria human challenge system that has transformed early stage drug development for malaria. Over his career he has made internationally significant contributions to the diagnosis and treatment of scabies, intestinal and extra-intestinal parasites. He leads the Infectious Diseases Program at QIMR Berghofer, an NHMRC Program Grant, and serves on a number of international editorial boards and advisory committees including WHO and the Bill and Melinda Gates Foundation.