Professor Zalcberg has made a significant contribution to improving cancer control in Australia. He has been involved in a broad range of activities that include the growth of the Peter MacCallum Cancer Centre into a centre of excellence nationally to supporting clinical trials, both as a clinician within the Australasian Gastro-intestinal Trials Group as well as in the development of processes that support all trials groups. He is highly regarded both nationally and internationally as a leader in his field and continues to play an active role in endeavours that aim to improve the quality of health care in Australia.