Professor Parker’s international reputation in protein crystallography reflects his astonishing output of more than 100 important protein structures. His pioneering studies of membrane-associated proteins are particularly significant, since such proteins are among the most challenging targets for protein crystallography and also important drug targets. The impact of his work has been amplified greatly through the ways he has used biological understanding and drug discovery to complement the structural information he has provided to collaborators. He has received several prestigious awards including the Ramaciotti Medal for Biomedical Research (2011) and was elected a Fellow of the Australian Academy of Science (2010).