Professor Sah has made seminal contributions to understanding the neural circuits underlying learning and memory formation in the mammalian brain. His pioneering studies have delineated the local circuits in the amygdala, a region of the brain critical in assigning emotional salience to events, as well as the receptors engaged during amygdala-dependent learning. He has also made significant discoveries regarding properties of the ion channels that underpin action potential generation, and demonstrated how these channels contribute to the discharge properties of central neurons and synaptic transmission. These findings have led to a clearer understanding of the pathology of anxiety-related disorders.